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Updated PubMed E-Utilities Now Live!

We’ve launched the updated version of E-Utilities API for PubMed. Thank you to all who tested the updated API on the test server and provided feedback.    This updated version now aligns the functions of the E-utilities with the web version of PubMed released in 2020. For example, search results returned by the updated ESearch E-utility will now match those … Continue reading Updated PubMed E-Utilities Now Live!

22 November 2022

NEW! Streamlining ClinVar Submission of Assertion Criteria

ClinVar is a freely available submission-driven database for information about genomic variation and its relationship to human health. ClinVar holds more than 1.5 million variants, and is powered by submitters around the world, who provide us with their assessments, the evidence, and the criteria they use to guide their interpretation process and come to their … Continue reading NEW! Streamlining ClinVar Submission of Assertion Criteria

18 November 2022

Re-evaluating the BLAST Nucleotide Database (nt)

The ongoing sequencing revolution has resulted in exponential growth of the NCBI BLAST databases. The default BLAST nucleotide database (nt), the most popular Web BLAST database, is currently 903 billion letters and continues to grow rapidly – doubling in size in the last year. This growth will cause longer search times, reduced capacity, and more … Continue reading Re-evaluating the BLAST Nucleotide Database (nt)

17 November 2022

RefSeq Release 215

RefSeq release 215 is now available online, from the FTP site and through NCBI’s Entrez programming utilities, E-utilities. This full release incorporates genomic, transcript, and protein data available as of November 7, 2022, and contains 335,372,031 records, including 244,583,657 proteins and sequences from 125,116 organisms. The release is provided in several directories as a complete dataset and also … Continue reading RefSeq Release 215

15 November 2022

Prokaryotic phylum name changes coming soon!

Beginning in the first week of January 2023, NCBI Taxonomy will initiate changes to prokaryote phylum names in accordance with the recent inclusion of rank ‘phylum’ in the International Code of Nomenclature for Prokaryotes (ICNP). We first announced this update that involves changes to 42 NCBI taxa about a year ago. We will change several names … Continue reading Prokaryotic phylum name changes coming soon!

14 November 2022

New and improved SciENcv experience starting January 2023!

Science Experts Network Curriculum Vitae (SciENcv) is an electronic system that helps you assemble professional information needed to apply for federal grant applications. Starting January 2023, we will be introducing a new and improved SciENcv experience! SciENcv helps you gather and compile information on expertise, employment, education, and professional accomplishments. You can use SciENcv to … Continue reading New and improved SciENcv experience starting January 2023!

10 November 2022

Submit your data to dbGaP in 3 easy steps!

Do you have human genetic data from a large-scale study? Submit your data to NCBI’s Database of Genotypes and Phenotypes (dbGaP) to contribute to meaningful discoveries about health. dbGaP contains data from more than 2.8 million study participants who have provided over 3.3 million molecular samples. How do I submit data to dbGaP? Step 1: … Continue reading Submit your data to dbGaP in 3 easy steps!

8 November 2022

CCDS Release 24

An updated dataset of human protein-coding regions from the Consensus Coding Sequence (CCDS) collaboration Are you interested in a set of high-quality human coding regions (CDS) with equivalent annotation in NCBI’s RefSeq and EMBL-EBI’s (European Molecular Biology Laboratories-European Bioinformatics Institute) Ensembl annotations? Check out the new CCDS Release 24! This CCDS set was generated by … Continue reading CCDS Release 24

2 November 2022

New annotations in RefSeq!

In August and September, the NCBI Eukaryotic Genome Annotation Pipeline released thirty-eight new annotations in RefSeq for the following organisms: Adelges cooleyi (spruce gall adelgid) Aethina tumida (small hive beetle) Anopheles aquasalis (mosquito) Anopheles maculipalpis (mosquito) Anthonomus grandis grandis (boll weevil) Aphis gossypii (cotton aphid) Bactrocera neohumeralis (fly) Bombus affinis (bee) Bombus huntii (bee) Cataglyphis hispanica (ant) Cygnus atratus … Continue reading New annotations in RefSeq!

31 October 2022

dbGaP: Data and analyses from millions of study participants, samples, and trillions of genotypes!

Are you familiar with the well-known Framingham Heart Study, a multi-generation study of residents of Framingham, Massachusetts begun in 1948? Much of what is now known about the impact of genetics, lifestyle, and diet on cardiovascular health and disease has come from this research study. (See PMC4159698  for a historical perspective.) Did you know that data from … Continue reading dbGaP: Data and analyses from millions of study participants, samples, and trillions of genotypes!

25 October 2022